Symbol Name ID |
Stag2
STAG2 cohesin complex component MGI:1098583 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Abnormality of the spleen |
Disease(s) Associated with STAG2 | |
holoprosencephaly |
Mouse Phenotypes | hematopoietic system phenotype |
enlarged spleen |
abnormal hematopoietic system morphology/development |
increased common myeloid progenitor cell number |
extramedullary hematopoiesis |
increased granulocyte monocyte progenitor cell number |
decreased common lymphocyte progenitor cell number |
decreased erythroid progenitor cell number |
increased red blood cell distribution width |
increased granulocyte number |
decreased B cell number |
increased monocyte cell number |
decreased leukocyte cell number |
increased hematopoietic stem cell number |
abnormal hematopoietic precursor cell morphology |
decreased megakaryocyte-erythroid progenitor cell number |
abnormal hematopoietic stem cell physiology |
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Availability | Mouse Genotype | |||||||||||||||||
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+ Stag2tm1.1Alos/Stag2tm1.1Alos (conditional) |
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Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+ Stag2tm1.1Alos/Y (conditional) |
* | |||||||||||||||||
Stag2tm1.1Soga/Y Tg(Mx1-cre)1Cgn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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