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Symbol
Name
ID
Stag2
STAG2 cohesin complex component
MGI:1098583
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormality of the spleen
Disease(s) Associated with STAG2
holoprosencephaly

Mouse Phenotypes
hematopoietic system phenotype
enlarged spleen
abnormal hematopoietic system morphology/development
increased common myeloid progenitor cell number
extramedullary hematopoiesis
increased granulocyte monocyte progenitor cell number
decreased common lymphocyte progenitor cell number
decreased erythroid progenitor cell number
increased red blood cell distribution width
increased granulocyte number
decreased B cell number
increased monocyte cell number
decreased leukocyte cell number
increased hematopoietic stem cell number
abnormal hematopoietic precursor cell morphology
decreased megakaryocyte-erythroid progenitor cell number
abnormal hematopoietic stem cell physiology
Availability Mouse Genotype
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
Stag2tm1.1Alos/Stag2tm1.1Alos  (conditional)
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
Stag2tm1.1Alos/Y  (conditional)
*
Stag2tm1.1Soga/Y
Tg(Mx1-cre)1Cgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory